The rat lungworm, Angiostrongylus (Parastrongylus) cantonensis, causes eosinophilic meningitis
in humans (4) and various disease manifestations (meningoencephalitis, neurologic disorders) in atypical host species, including wildlife and captive animals (5).
Human infection typically manifests as acute eosinophilic meningitis
or meningoencephalitis; in up to 30% of cases there is a peripheral eosinophilia.
He also has been involved in clinical research on the parasite, Angiostrongylus cantonensis, responsible for most cases of eosinophilic meningitis
Other symptoms are specific to organs involved and include hepatic granulomas, chronic prurigo, pruritus, urticaria, eczema, vasculitis, eosinophilic meningitis
or encephalitis, myelitis, optic neuritis, radiculitis, cranial nerve palsy, and, less commonly, myocarditis, nephrotic syndrome, and arthritis.
The organism most commonly causing eosinophilic meningitis
is a rat lung worm called angiostrongylus cantonensis.
Angiostrongylus cantonensis, a nematode that is the most common infectious cause of eosinophilic meningitis
and meningoencephalitis both worldwide and in areas of Southeast Asia and many Pacific Islands, is one of the most important zoonotic parasites in Taiwan (1, 2).
Full recovery from Baylisascaris procyonis eosinophilic meningitis
1) As humans are accidental hosts, the parasite cannot complete its life cycle, and immature worms lodge in the central nervous system where they elicit a condition known as eosinophilic meningitis
An outbreak of eosinophilic meningitis
caused by the roundworm Angiostrongylus cantonensis has been reported among 12 young adults from the United States who visited Jamaica in 2000.
infection is usually seen as self-limited eosinophilic meningitis
and only rarely causes severe disease with prominent spinal or cerebral involvement (1).
Although public health authorities should consider implementation of surveillance and control strategies to reduce the populations of snail and rat hosts, a better understanding is needed of the epidemiologic significance of these findings, which can be attained through studies to identify human cases of eosinophilic meningitis
in the region.
cantonensis that can cause eosinophilic meningitis