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Epigenetic |
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Out side factors during development can change which DNA segments are epigenetically modified, setting the stage for traits that linger into adulthood. Therefore, environmental factors that affect DNA methylation patterning during development can potentially influence adult phenotype via alterations in CpG methylation at epigenetically labile regions in the genome. A seminal finding that monozygotic twins are epigenetically indistinguishable early in life but, with age, exhibit substantial differences in epigenetic markers underscores the important role played by the environment in shaping the epigenome (Fraga et al. |
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