M2 PHARMA-March 9, 2018-Neflamapimod Improves Episodic Memory
in Early Alzheimer's Disease
The hippocampus is the region of the brain primarily associated with spatial and episodic memory
, a key factor in long-term cognitive health.
The results indicated that there was a small association between age-related hearing loss and increased risk for cognitive decline (such as in executive function, episodic memory
and processing speed), cognitive impairment and dementia.
But times tasks, speed of information processing, recognition memory, episodic memory
, spatial abilities, and working memory decline drastically with age.
Methods: 40 patients with insomnia (insomnia group) and 48 normal sleepers (control group) were tested using the Pittsburgh Sleep Quality Index (PSQI), episodic memory
test, and Montreal Cognitive Assessment (MoCA).
ThinkBlue is a new enhanced extract of wild blueberry that is associated with episodic memory
It is important to be mindful of the components of memory, particularly the distinction of semantic and episodic memory
The participants' cognitive function was measured using interview-based standard assessments that evaluated episodic memory
, visuospatial abilities, attention, and orientation.
This will be based on state-of-the-art neuroimaging technology, in combination with a novel sensitive neuropsychological test that detects subtle alterations in episodic memory
, which has been validated for our cohort.
To test whether the timing of estrogen therapy affected the primary cognitive endpoint of verbal episodic memory
, the researchers conducted ELITE (Early vs.
The main ELITE trial tested the effect of the timing of estradiol, compared with placebo, on the progression of subclinical atherosclerosis, whereas the ELITE-Cog trial assessed the effects of the timing of estradiol on a composite test of verbal episodic memory
The episodic memory
tested in the rodents was the memory of an aversive experience: a mild foot shock received upon entering in a new place.