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A segment of DNA in certain cells, especially bacterial cells, that can exist either autonomously in the cytoplasm or as part of a chromosome.

ep′i·so′mal adj.
ep·i·so′mal·ly adv.


(Microbiology) in the manner of an episome
References in periodicals archive ?
There -- as the successor of Vivocell - it harbors over 2500 licensed unrelated cord blood units and various episomally reprogrammed iPS cells and hepatocytes generated.
Mehta et al (37) used a Leishmania mutant episomally transfected with enhanced green fluorescent protein, enabling in vivo real-time whole-body fluorescence imaging, to follow the progression of Leishmania infection in parasitized tissues.
The HIV genome does not replicate episomally, but depends on integration into the host genome for replication.