BNP immunoreactivity was analyzed using 2 sandwich immunoassays: one utilizing monoclonal antibody (mAb) KY-BNP-II (epitope
14-21) as capture with mAb 50E1 (epitope
26-32) for detection and a single-epitope
sandwich BNP (SES-BNP) immunoassay specific to the epitope
One major advantage of anti-peptide antibodies produced against MAPs is that they are targeted against single epitope
and presumably could serve as homogenous antibodies similar to monoclonal antibodies.
It is encouraging to see that this kit may have a potential role in future clinical management of CRPC patients, leading to better monitoring and possibly improved survival rates," said Ping Gao, President of Epitope
The researchers took known IgE binding sites (epitope
sequences) from peanut and nut proteins and ran those through the SDAP database in order to predict cross-reactive epitopes
in other nuts.
VSFNQNLEY of NA protein was excellent MHC I promiscuous binder at average binding score 111.
The two HIV-1 gp41 sequences used in this analysis containing neutralizing epitope
have been submitted to Genbank under the following accession IDs: EU569806, EU569820.
31, researchers describe a new "epitope
-mapping" laboratory test that within three weeks can pinpoint the unique binding site - or epitope
- from any antigen where immune system T cells can most securely attach and attack invading germs or errant cells.
All of these HLA-DRB1 alleles increasing risk of RA share common QKRAA, QRRAA and RRRAA amino acid sequences termed the shared epitope
(SE) at positions 70-74.
Second, the epitopes
are MHC class I antigen-restricted, which means that only a fraction of the human population will possess the correct MHC class I molecules capable of presenting a specific epitope
and eliciting appropriate and protective CMI responses.
The second edition of this research guide for epitope
mapping protocols is designed for immunologists, structural biologists and biotechnologists who need to familiarize themselves with the latest methods for mapping B-cells, T-cells, antibodies and antibody profiling signatures in biological fluids.
JPT offers four delivery options for T-cell assays: 1) Fast Track for proteome-wide T-cell epitope
discovery programs 2) Research Track for T-cell epitope
mapping studies 3) Discovery Track for immune monitoring applications and 4) Trial Track for vaccination trials.
The rice is specially developed using MAT vector system, a bio technology for genetically extracting the necessary genomes, in this case an epitope
into the rice.