Estranger

es·trange  (-strnj)

tr.v. es·tranged, es·trang·ing, es·trang·es

1. To make hostile, unsympathetic, or indifferent; alienate.

2. To remove from an accustomed place or set of associations.

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[Middle English estraungen, from Old French estrangier, from Latin extrnere, to treat as a stranger, disown, from extrneus, foreign; see strange.]

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es·trangement n.

es·tranger n.

Synonyms: estrange, alienate, disaffect
These verbs refer to disruption of a bond of love, friendship, or loyalty. Estrange and alienate are often used with reference to two persons whose harmonious relationship has been replaced by hostility or indifference: Political disagreements led to quarrels that finally estranged the two friends. His persistent antagonism alienated his wife.
Disaffect usually implies discontent, ill will, and disloyalty within the membership of a group: Colonists were disaffected by the royal governor's actions.