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estrogen antagonist

   Also found in: Encyclopedia, Wikipedia, Hutchinson 0.06 sec.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.estrogen antagonist - an antagonist for estrogen that is used in the treatment of breast cancer
tamoxifen
antagonist - a drug that neutralizes or counteracts the effects of another drug


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The estrogen antagonist ICI 164384, for example, attenuates the effects of cadmium on gene expression.
Understanding sex differences in environmental health: a thought ... by Marts, Sherry A. / Environmental Health Perspectives
57-63-6), and the reference estrogen antagonist was the pure antagonist ZM 189,154 (ZM; CAS no.
The OECD program to validate the rat uterotrophic bioassay to screen ... by Owens, William / Environmental Health Perspectives
However, we cannot rule out that newly identified receptors such as SXR and PXR [reviewed by Blumberg and Evans (62)], which are activated by a variety of different compounds, including estrogen antagonists and agonists, could be involved in the activation/repression of some of the estrogen-sensitive genes we have identified.
Assaying Estrogenicity by Quantitating the Expression Levels of ... by Leffers, Henrik / Environmental Health Perspectives
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