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etanercept

   Also found in: Medical, Wikipedia 0.06 sec.
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Noun1.etanercept - a genetically engineered anti-TNF compound (trade name Enbrel) consisting of receptors that bind TNF; it is injected twice a week in the treatment of rheumatoid arthritis
anti-TNF compound - a class of drugs that block the action of tumor necrosis factor (TNF); used in cases of rheumatoid arthritis because TNF instigates inflammation of the joints


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The drugs come in two categories: traditional disease modifying anti-rheumatic drugs (DMARDs) like methotrexate, sulfasalzine (Azulfidine), leflunomide (Arava) and hydroxychloroquine (Plaquenil); and, for those who don't respond to DMARDs, biologic agents like TNF blockers adalimumab (Humira), etanercept (Enbrel) and infliximab (Remicade), or the newer biologic
To test this idea, Holgate and his colleagues administered the drug etanercept (Enbrel[R]) to 17 subjects with severe asthma in a 12-week study.
Rather, the patients received etanercept, an anti-inflammatory arthritis medication, and two other drugs that fight rejection, the researchers report in the Feb.
 
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