Antiviral therapy with acyclovir, valacyclovir, and famciclovir
is the backbone of management of most symptomatic patients with herpes.
, the prodrug of penciclovir, is more effective than valacyclovir at resolving acute herpes zoster rash and shortening the duration of PHN.
The most commonly used and current gold standard initial treatment for ARN is acyclovir; other antiviral options including valacyclovir, famciclovir
, ganciclovir, valganciclovir, and foscarnet are also used.
Acyclovir (Zovirax[R]), famciclovir
(Famvir[R]), and valacyclovir (Valtrex[R]) are systemic antiviral medications prescribed for herpes zoster, genital herpes, and mucosal herpes in immunocompromised individuals (Vallerand, Sanoski, & Deglin, 2017).
Antiviral drugs, including acyclovir, famciclovir
and valacyclovir, decrease pain, inhibit viral replication and shedding, promote healing of lesions, and attenuate the severity of discomfort and neuralgia.
The treatment of herpes zoster infections consists of antiviral agents such as acyclovir, valacyclovir, and famciclovir
Food and Drug Administration (FDA) for the treatment of acute HZ; they are acyclovir, famciclovir
, and valacyclovir.
Outside biopsy was done which showed non-specific inflammatory dermatitis and he was treated in the lines of genital herpes infection by private practitioners with tab Acyclovir 800 mg tid for 1 month; Famciclovir
500 mg twice daily for 1 wk.
Drugs include acyclovir, famciclovir
, and valacyclovir are prescribed for genital herpes therapy and based on the condition drugs are given to patient orally and intravenously.
and valacyclovir possess more efficient pharmacokinetic profiles, and are just as safe and well tolerated.
No available antiviral drug can eradicate herpes virus from the body completely, and the current antiviral drug for HSV infections management is based on nucleoside analogues that inhibit the viral DNA polymerase as acyclovir, valacyclovir, famciclovir
and penciclovir and their derivates (Donalisio et al.
He used topical ganciclovir eye gel, interferon, levofloxacin, pranoprofen eye drops, deproteinized calf blood extract eye gel, and oral famciclovir