Neurologic signs of infection in horses are similar for both lineages and include ataxia, weakness, recumbence, seizures, and muscle fasciculation
(muscle twitches) in the arm, leg, shoulder, or tongue.
Physical examinations must be completed by examining deep tendon reflexes (DTRs), muscle tones, proximal or distal muscle strengths, and presence of fasciculation
, sensory deficits or muscle atrophy.
Among all patients, 44% (22 cases) had muscle weakness or fasciculation
with mean serum [K+] of 3.
The Gower sign, calf pseudohypertrophy, or fasciculation
was not observed, and there was no tenderness or discomfort on palpation.
To further confirm the differential gene expression obtained from the sequencing data, we analyzed by quantitative RT-PCR the expression levels of ATP synthase subunit alpha 1 (ATP5A1), fasciculation
and elongation protein zeta-2 (FEZ2), MHC class I antigen alpha chain (HLA-A), and MHC class II beta chain 1 (BLB1) genes, which were mainly involved in metabolism and immune defense.
We are also intrigued by recent data from independent researchers at NYU and Mount Sinai that implicate TRPA1 ion channelopathy in cramp fasciculation
syndrome, said Flex Pharma R&D President Bill McVicar, Ph.
The medical history of patient indicated that one month before the admission to our hospital, the patient had experienced confusion, hallucinations, hypersalivation, pallor, palpitation, sweating, dyspnea, involuntary urination and defecation, muscle fasciculation
and piloerection symptoms, 20 minutes after ingestion of approximately 40 mL chlorpyrifos with the intent to commit suicide.
Muscarinic symptoms such as nausea, vomiting, diarrhea, sweating, salivation, urination, stool incontinence, lacrimation, miosis, and bradycardia and nicotinic signs such as mascular weakness, fasciculation
, paralysis, convulsion, and coma are found.
of a single motor unit of a muscle, muscle wasting or a squint could indicate a mononeuropathy.
At examination, she showed bilateral severe facial muscle and tongue atrophy and fasciculation
of the tongue and left side ptosis.
IA = insertional activity, Fasc = fasciculation
, Fib = fibrillation, HF = high-frequency potentials, L = lumbar, N = normal, PPP = polyphasic potentials, PSP = pro- gressive supranuclear palsy, PSW = positive sharp waves, S = sacral.