To the Editor: Human fascioliasis
, infection with Fasciola spp.
Ogunrinade AF and BI Ogunrinade Economic importance of bovine fascioliasis
Here, we provide results of veterinary interest as regards the possibility of reducing transmission of the liver fluke Fasciola gigantica (Cobbold), a cause of bovine fascioliasis
, the widely distributed snail Radix natalensis being one of the intermediate hosts in Africa as well as in tropical regions of southern and south-eastern Asia.
Focusing on the helminth that causes animal and human fascioliasis
(liver fluke disease), we will turn-the-table on this parasite by targeting its immunomodulatory mechanisms and develop vaccine formulations that induce potent protective Th1-inducing humoral and cellular immune responses.
, liver lesions may be present and bile ducts may be observed as thickened and dilated in tomography (7), (8).
1 Buruli Ulcer, Chagas disease (American trypanosomiasis), Cysticercosis, Dengue/Severe dengue, Dracunculiasis (guinea-worm disease), Echinococcosis, Fascioliasis
, Human African trypanosomiasis, Leishmaniasis, Leprosy, Lymphatic filariasis, Onchocerciasis, Rabies, Schistosomiasis, Soil transmitted helminthiasis, Trachoma, Yaws
is a major zoonosis that causes a great deal of economic loss throughout the tropical region of the world .
Clinico-pathological studies on naturally-occurring bovine fascioliasis
in the Sudan.
In Britain, fascioliasis
disease is caused mainly by a trematode parasite called fasciola hepatica.
Oxyclozanide is a safe and effective flukicide administered to cattle, buffaloes, sheep and goats for the treatment and control of fascioliasis
The clinical differential diagnosis of hepatic strongyloidiasis includes other parasitic and malignant diseases which cause hypereosinophilia (eg, fascioliasis
, echinococcosis, schistosomiasis).
The diseases targeted by the pool are the 16 diseases identified by the FDA for its own Neglected Tropical Diseases (NTD) initiative: tuberculosis, malaria, blinding trachoma, buruli ulcer, cholera, dengue/dengue haemorrhagic fever, racunculiasis, fascioliasis
, human African trypanosomiasis, leishmaniasis, leprosy, lymphatic filariasis, onchocerciasis, schistosomiasis, soil transmitted helminthiasis, and yaws.