For instance, grapefruit or orange juice lowers the oral bioavailability of several drugs transported by OATP1A2 such as celiprolol and fexofenadine
His preferred histamine-1 /histamine-2 blocker is fexofenadine
because it doesn't cross the blood-brain barrier.
(Allegra) is the only antihistamine that doesn't permeate the blood-brain barrier and therefore cannot bind to CNS [histamine.
Key Words: antihistamine, seasonal allergic rhinitis, desloratadine, cetirizine, fexofenadine
The researchers found that Butterbur was as effective as fexofenadine
in relieving a drippy nose, sneezing, nasal congestion, and itchy eyes.
is indicated for use in children aged 6 years and older, loratadine for children 2 years or older, cetirizine for children 6 months and older, and azelastine for children 5 years and older.
cetirizine HCl 10 mg daily, fexofenadine
HCl 180 mg daily, and placebo in
1) Newer drugs, such as fexofenadine
(Allegra), loratadine (Claritin) and cetirizine (Zyrtec), all taken in pill form, as well as the intranasal antihistamine azelastine (Astelin), and ketotifen, an antihistamine drop for your eyes, are less sedating and thus the treatment of choice.
1 percent, (b) taking the popular prescription antihistamine, fexofenadine
(Allegra), or (c) taking a placebo.
I don't have one particular favourite, but most of my patients take fexofenadine
(Telfast - a safer version of Triludan) or loratidine (Clarityn).
Testing the in-vitro action of grapefruit juice on the absorption of a variety of drugs that included cyclosporine, vinblastine, losartan, digoxin, and fexofenadine
, the investigators discovered that the juice reduced absorption of all.
In July, the FDA approved Allegra, known generically as fexofenadine