The trial will recruit patients with Overgrowth Diseases such as PROS (PIK3CA-Related Overgrowth Spectrum), which includes orphan diseases such as CLOVES (Congenital Lipomatous Overgrowth, Vascular malformations, Epidermal nevi, Spinal/skeletal anomalies and/or scoliosis) and Fibroadipose
hyperplasia, as well as Proteus syndrome.
Histopathological finding of scar mass showed fibrocollagenous tissue as well as fibroadipose
tissue with normal endometrial glands and stroma.
Open biopsy showed benign fibroadipose
tissue (C) and benign lamellar bone (D).
Histopathology of the biopsy revealed fibroadipose
and fibrocollagenous tissue, showing dense chronic inflammation along with the formation of lymphoid follicles.
The nodules were excised under general anaesthesia and histopathology investigation revealed fibrocollagenous and fibroadipose
tissue exhibiting endometrial glands surrounded by endometrial type stroma consistent with scar endometriosis.
18,21) This presentation contrasts with typical normal muscle appearing as a hypoechoic background of muscle fascicles separated by clearly demarcated linear hyperechoic strands representing fibroadipose
Microscopically, the sections showed a diffusely enlarged lymph node and adjacent fibroadipose
The central neck dissection included the comprehensive, compartment-oriented removal of all fibroadipose
tissue between the trachea and carotid sheath from the hyoid bone superiorly and the upper mediastinum and the subclavian or innominate artery inferiorly.
ARVD is defined by progressive replacement of healthy tissue of cardiac muscle, mainly in the right ventricle, with fibroadipose
tissue and enhanced apoptosis of cardiomyocytes.
Pathology revealed a malignant neoplasm with variable morphology and extensive infiltration of adjacent fibroadipose
and muscle tissue.
Histologic examination of the hernia sac revealed fibroadipose
tissue with multiple foci of infiltrative, malignant glands with papillary architecture (Figure 2).
INTRODUCTION: Fibrolipomatous hamartoma which is a rare benign tumor, characterized by an anomalous overgrowth of fibroadipose
tissue between and around nerve bundles, which causes enlargement of the affected nerve and form a palpable neurogenic mass.