complement fixation

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Related to fixation reaction: complement fixation reaction

complement fixation

n.
The binding of active serum complement to an antigen-antibody pair. It is the basis for various diagnostic tests to detect the presence of a specific antigen or antibody.

com′plement fixa`tion



n.
the binding of complement to immune complexes or to certain foreign surfaces, as those of invading microorganisms.
[1905–10]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.complement fixation - an immune response in which an antigen-antibody combination inactivates a complement (so it is unavailable to participate in a second antigen-antibody combination)
immune reaction, immune response, immunologic response - a bodily defense reaction that recognizes an invading substance (an antigen: such as a virus or fungus or bacteria or transplanted organ) and produces antibodies specific against that antigen
References in periodicals archive ?
Serological response of patients suffering from primary and recrudescent typhus: comparison of complement fixation reaction, Weil-Felix test, microimmunofluorescence, and immunoblotting.
In both instances, Melott's group found evidence that the Haber process - whereby a nitrogen fixation reaction produces ammonia - may have occurred on a large scale.
The unusually large amount of copper and arsenic leached from the heart wood could be explained by the deposition of CCA fixation reaction products in the cell lumens due to higher extractive levels where they would be more readily accessible to leaching (Cooper et al.