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frameshift mutation
(redirected from frameshift mutations)

   Also found in: Encyclopedia, Wikipedia 0.05 sec.
frame·shift mutation (frmshft)
n.
A mutation in a DNA chain that occurs when the number of nucleotides inserted or deleted is not a multiple of three, so that every codon beyond the point of insertion or deletion is read incorrectly during translation.


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These include frameshift mutations caused by nucleotide insertion or deletion, as well as missense, nonsense, and splice site mutations (Abramowicz et al.
 
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