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A section of DNA that contains the genetic code for a single polypeptide and functions as a hereditary unit.

[From cis-trans test, a genetic test (cis- + trans-) + -on.]

cis·tron′ic adj.


(Genetics) genetics the section of a chromosome that encodes a single polypeptide chain
[C20: from cis-trans; see cis-trans test]


(ˈsɪs trɒn)

a segment of DNA that codes for the formation of a specific protein; a structural gene.
[1955–60; cis- + tr (ans)- + -on1]
cis•tron′ic, adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cistron - (genetics) a segment of DNA that is involved in producing a polypeptide chaincistron - (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"
dominant gene - gene that produces the same phenotype in the organism whether or not its allele identical; "the dominant gene for brown eyes"
allele, allelomorph - (genetics) either of a pair (or series) of alternative forms of a gene that can occupy the same locus on a particular chromosome and that control the same character; "some alleles are dominant over others"
genetic marker - a specific gene that produces a recognizable trait and can be used in family or population studies
homeotic gene - one the genes that are involved in embryologic development
lethal gene - any gene that has an effect that causes the death of the organism at any stage of life
linkage group, linked genes - any pair of genes that tend to be transmitted together; "the genes of Drosophila fall into four linkage groups"
modifier gene, modifier - a gene that modifies the effect produced by another gene
mutant gene - a gene that has changed so that the normal transmission and expression of a trait is affected
nonallele - genes that are not competitors at the same locus
operator gene - a gene that activates the production of messenger RNA by adjacent structural genes
oncogene, transforming gene - a gene that disposes normal cells to change into cancerous tumor cells
polygene - a gene that by itself has little effect on the phenotype but which can act together with others to produce observable variations
proto-oncogene - a normal gene that has the potential to become an oncogene
recessive gene - gene that produces its characteristic phenotype only when its allele is identical; "the recessive gene for blue eyes"
regulator gene, regulatory gene - a gene that produces a repressor substance that inhibits an operator gene
repressor gene - gene that prevents a nonallele from being transcribed
structural gene - a gene that controls the production of a specific protein or peptide
suppresser gene, suppressor gene, suppresser, suppressor - a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene)
transgene - an exogenous gene introduced into the genome of another organism
X-linked gene - a gene located on an X chromosome
holandric gene, Y-linked gene - a gene located on a Y chromosome
chromosome - a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order; "humans have 22 chromosome pairs plus two sex chromosomes"
genetic science, genetics - the branch of biology that studies heredity and variation in organisms
molecular biology - the branch of biology that studies the structure and activity of macromolecules essential to life (and especially with their genetic role)
sequence - serial arrangement in which things follow in logical order or a recurrent pattern; "the sequence of names was alphabetical"; "he invented a technique to determine the sequence of base pairs in DNA"
deoxyribonucleic acid, desoxyribonucleic acid, DNA - (biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information; "DNA is the king of molecules"
References in periodicals archive ?
Gene therapy, using modified DNA to introduce a functional gene to replace the mutated gene causing the blood disorder, offers additional possibilities for a cure beyond bone marrow transplants.
These results suggest sirtuin related miR-373-3p have association with severity of CAD and may be a target for therapeutic intervention of CAD and also further evaluation by functional gene expression study recommended as the study is going on now.
Pre-clinical data in animal models of GM1 show that LYS- GM101 treatment delivers a functional gene encoding the [sz]gal enzyme resulting in a reduction of GM1 gangliosides and transforms the animal phenotype.
Ready-to-package plasmid libraries consist of GeCKO libraries; target all exons in the human or mouse genome; and have been validated by researchers studying functional gene interactions on an -omics scale.
The functional gene is inserted into a vector, containing a small DNA sequence, that acts as a delivery mechanism, providing the ability to deliver the functional gene to cells.
The current pipeline for gene therapies is diverse in terms of the approaches and vectors covered; 50% are gene silencing therapies, while 31% involve the insertion of a functional gene -
This pattern is comparable to another Y-chromosomelinked functional gene, the male sex determining locus, SRY (Tucker and Lundrigan 1993; Whiteld, Lovell-Badge, and Good fellow 1993; Pamilo and O'Neill 1997; Wang, Zhang, and Zhang 2002, Hussain et al.
The topics include measuring and characterizing biomass structure and processing, technologies to study plant biomass fermentation using the model bacterium Clostridium phytofermentans, functional gene resources from cellulose-feeding insects for novel catalysts, Tipula abdominalis as a natural biorefinery with novel microbial enzymes useful for pectin-rich biomass deconstruction, and the techno-economic analysis and life-cycle assessment of converting lignocellulosic biomass to sugars using various pre-treatment technologies.
Metagenomic data and 16S amplicons were most useful for assessing seasonal shifts in microbial assemblages, while metatranscriptome data appeared to better reflect diurnal rhythms seen across functional gene categories.
Basically, you can alter your gene expression--the process by which inheritable information from a gene is translated and made into a functional gene product in the cell--and thus suppress the path of disease.
EMs have 2 functional gene copies and UMs have >2 functional genes from gene duplication, resulting in ultra-rapid metabolism.

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