MNPs-Fe[sub]3O[sub]4 have been successfully loaded with doxorubicin,[sup], wogonin,[sup], and gambogic
Synthesis and antiangiogenic activity of novel gambogic
acid (GA) has anticancer effect and anti-proliferative activity which is extracted from a dried yellow resin of the Garcinia hanburyi Hook.
Other spice-derived phytochemicals, such as capsaicin, cardamonin, dibenzoylmethane, diosgenin, gambogic
acid, gingerol, thyoquinone, urosolic acid and zerumbone have been show the ability to suppress NF-kB activation in a similar manner.
Maxim researchers initially identified gambogic
acid as the ligand for binding and activating this pathway.
acid enhances the radiosensitivity of human esophageal cancer cells by inducing reactive oxygen species via targeting Akt/mTOR pathway.
Poloxamer 407/TPGS mixed micelles for delivery of gambogic
acid to breast and multidrug-resistant cancer.
Maxim Pharmaceuticals (Nasdaq:MAXM)(SSE:MAXM) announced the publication of its manuscript entitled "Discovery, Characterization and SAR of Gambogic
Acid as A Potent Apoptosis Inducer by a HTS Assay.
acid was found to inhibit PI3K/mTOR pathway in myeloma cells.
Maxim's Director, Cell Biology, in a presentation entitled "Discovery of Gambogic
Acid and Derivatives as Apoptosis-Inducing Natural Products with Novel Mechanism of Action and Potent In Vivo Anti-Tumor Activity.
acid triggers DNA damage signaling that induces p53/p21Wafl/CIPl activation through the ATR-Chk1 pathway.
Proteomic identification of molecular targets of gambogic
acid: role of stathmin in hepatocellular carcinoma.