The diagnosis of Plasmodium species infection was made by either with detection of gametocyte
of PF and PV from Giemsa-stained peripheral blood smear or rapid diagnostic test (RDT).
Identifying factors associated to timely treatment can strengthen the strategies for malaria control program, especially considering the expected impact on gametocyte
availability for malaria vectors.
Increased Plasmodium falciparum gametocyte
production in mixed infections with P.
Many treatments (even some that are not permanently gonadotoxic) can trigger transient changes in in gametocyte
DNA, along with changes in number and function.
(crescent or sausage shaped).
Despite this, through the observations, Plasmodium falciparum prevalence and gametocyte
rate in villagers decreased dramatically after LLINs deployment (61).
The selected proteins are very important because PfLDH has a role in glycolysis for energy production during asexual cycle, while Pfg27 is vital protein for the gametocyte
production during sexual phase of the parasite; thus both proteinsare potential molecular targets for antimalarial drugs.
In teleostean fish, photoperiod influences the hypothalamic-pituitary-gonadal axis stimulating or inhibiting the production of gonadotropin-releasing hormone, pituitary hormones (follicle stimulating hormone and luteinizing hormone) and other hormones that modulate reproduction and gametocyte
maturation (DAVIE et al.
falciparum is evenly expressed in asexual blood-stage parasites during development from merozoites via trophozoites to schizonts, as well as in the sexual gametocyte
Previous methods used human gametocyte
donors to infect mosquitoes intended to deliver sporozoites to vaccines, (7) but this method was unpredictable and dependent on the availability of people naturally infected with malaria as gametocyte
cerevisiae); MON1B, MON1 secretory trafficking family member B; SYCE1L, synaptonemal complex central element protein 1-like; VN2R10P, vomeronasal 2 receptor 10 pseudogene; PTPRT, protein tyrosine phosphatase, receptor type, T; PPIAP21, peptidylprolyl isomerase A (cyclophilin A) pseudogene 21; IFT52, intraflagellar transport 52; MYBL2, v-myb avian myeloblastosis viral oncogene homolog-like 2; GTSF1L, gametocyte
specific factor 1-like; JPH2, junctophilin 2; FITM2, fat storage-inducing transmembrane protein 2; R3HDML, R3H domain containing-like; HNF4A, hepatocyte nuclear factor 4, alpha; MIR3646, microRNA 3646; TTPAL, tocopherol (alpha) transfer protein- like; SERINC3, serine incorporator 3; PKIG, protein kinase (cAMP- dependent, catalytic) inhibitor gamma; ADA, adenosine deaminase.
dynamics and the role of drugs in reducing the transmission potential of Plasmodium vivax.