ganglioside


Also found in: Medical, Encyclopedia, Wikipedia.
Related to ganglioside: cerebroside

gan·gli·o·side

 (găng′glē-ə-sīd′)
n.
Any of a group of galactose-containing cerebrosides found in the surface membranes of nerve cells.

ganglioside

(ˈɡæŋɡlɪəʊˌsaɪd)
n
any of several glycolipids found in the plasma membrane of certain cells

gan•gli•o•side

(ˈgæŋ gli əˌsaɪd)

n.
any of a group of glycolipids abundant in nerve ganglia.
[1940–45; gangli (on) + -ose2 + -ide]
References in periodicals archive ?
Objective: To study the clinical effect of ganglioside (GM) and fructose-1, 6-diphosphate (FDP) on neonatal heart and brain injuries after asphyxia.
Role of cholesterol and the ganglioside GM1 in entry and short-term survival of Brucella suis in murine macrophages.
In addition, nerve growth factor, ganglioside, and citicoline can also be tried.
Ganglioside profiles of metastases and of metastasizing and nonmetastasizing rat primary mammary carcinomas.
A monoclonal antibody-defined antigen associated with gastrointestinal cancer is a ganglioside containing sialylated lacto-N-fucopentaose II.
Pre-clinical studies of ERT for GM2 gangliosidoses have been conducted using a recombinant modified Hex-B produced in Chinese Hamster Ovary (CHO) cells, which allowed in-vitro GM2 ganglioside storage reduction and in the parenchyma of intracerebroventricularly injected mice [5].
20) The high amount of Sia secretion in milk shortly after child-birth may mirror the high rate of ganglioside biosynthesis of the brain of human and rat newborns and milk Sia is a supplementary source of glyco-conjugate-bound brain Sia.
4] An autoimmune attack is thought to be occurring against GM1 ganglioside in peripheral nerves.
The finding that HDI offers no survival benefit contradicts an earlier study (ECOG E1694) that compared HDI with ganglioside vaccine treatment.
Fine specificity of natural killer T cells against GD3 ganglioside and identification of GM3 as an inhibitory natural killer T-cell ligand," Immunology, vol.
Monosialic ganglioside GM3 specifically suppresses the monocyte adhesion to endothelial cells for inflammation," The International Journal of Biochemistry & Cell Biology, vol.
Unituxin reacts specifically with the ganglioside GD2, which is highly expressed on the surface of the neuroblastoma cells and minimally expressed on the surface of normal human neurons, peripheral pain fibres, and skin melanocytes.