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gastrin

   Also found in: Medical, Wikipedia 0.04 sec.
gas·trin  (gstrn)
n.
A hormone secreted by glands in the mucous membrane of the stomach that stimulates the production of gastric juice.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.gastrin - polypeptide hormone secreted by the mucous lining of the stomach; when peptides and amino acids are present in the small intestine the secretion of gastric acid is stimulated
gastrointestinal hormone, GI hormones - hormones that affect gastrointestinal functioning


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Six of the mice lacking gastrin developed stomach tumors at 12 months of age, but none of normal mice did, the researchers report in the March 31 Oncogene.
Aphton's anti-gastrin targeted therapy induces antibodies in patients that bind to both gastrin 17 and gly-gastrin and remove them from circulation before they can bind to the cancer cell and initiate cell growth.
They secrete a substance called gastrin that causes the stomach to produce too much acid, which in turn causes the stomach and duodenal ulcers (peptic ulcers).
 
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