gemfibrozil


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gem·fi·bro·zil

 (jĕm-fī′brə-zĭl, -fĭb′rə-)
n.
A drug, C15H22O3, used to treat high levels of triglycerides and low levels of HDL.

[gem-, origin unknown + fibr(ate), class of lipid-lowering drugs + alteration of xyl(ene).]

gemfibrozil

(dʒɛmˈfaɪbrəʊzɪl)
n
(Pharmacology) a drug that lowers the concentration of low-density lipoproteins in the blood and is therefore used to treat patients with hyperlipoproteinaemia
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.gemfibrozil - medication (trade name Lopid) used to lower the levels of triglyceride in the blood
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
Translations

gemfibrozil

n gemfibrozilo
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References in periodicals archive ?
Manufacturer package inserts have started indicating that statins should be used at a low dose when combined with gemfibrozil.
Among fibric acid derivatives, only gemfibrozil (Lopid) has some human data.
Patients were randomly assigned (by chance, like flipping a coin) to receive gemfibrozil (Lopid), a drug used to treat dyslipidemia (37 patients); metformin (Glucophage), a drug used to treat insulin resistance (35 patients); or a placebo (36 patients).
When drugs become necessary, we recommend as initial therapy pravastatin or atorvastatin for elevated low-density lipoprotein cholesterol levels and gemfibrozil or fenofibrate when triglyceride concentrations exceed 500 mg/dL.
In the current Baycol litigation, the focus is primarily on the coprescription of Baycol and gemfibrozil for patients with severe cholesterol abnormalities and on the use of a higher strength of Baycol (0.
A November 1998 label change stated that patients should not take the drug with gemfibrozil, a medication often used in combination with the other statins to help lower cholesterol.
Fatal rhabdomyolysis was reported most frequently when used in higher doses, with elderly patients, and when taken with gemfibrozil (Lopid[R] and generics).
Health officials determined Baycol carried a higher risk than similar drugs for producing kidney failure and the muscle disease rhabdomyolysis, especially for patients who also took the drug gemfibrozil (Lopid).
Among those drugs that survived passage through waste-treatment facilities--but not drinking-water-treatment plants--were diltiazem, which is used to regulate blood pressure; metformin, an antidiabetes drug; gemfibrozil, a cholesterol-lowering drug; and dehydronifedipine, a breakdown product of a drug for angina.
Bayer said the drug, named Baycol, could cause muscle destruction if taken together with gemfibrozil, another cholesterol-lowering drug.