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gene amplification

   Also found in: Medical, Legal, Encyclopedia, Wikipedia, Hutchinson 0.04 sec.
gene amplification
n.
A cellular process characterized by the production of multiple copies of a particular gene or genes to amplify the phenotype that the gene confers on the cell. Drug resistance in cancer cells is linked to amplification of the gene that prevents absorption of the chemotherapeutic agent by the cell.
gene amplification
An increase in the number of copies of a gene in a cell, resulting in an elevation in the level of the RNA or protein encoded for by the gene and a corresponding amplification of the phenotype that the gene confers on the cell. Drug resistance in cancer cells is linked to amplification of the gene that prevents absorption of the chemotherapeutic agent by the cell.


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? Mentioned in ? References in periodicals archive
 
Tokyo, Japan, Apr 21, 2006 - (JCN) - Sysmex announced on April 20 that it will introduce the gene amplification detector RD-100i and related reagents in the European market.
Sysmex to Introduce New Analyzer for Detecting Breast Cancer ... by JCNN News Summaries
The alliance also includes the development of highly sensitive, selective and portable detection systems that combine Nanosphere's proprietary nanoparticle DNA probe technology with Takara's proprietary ICAN(TM) isothermal gene amplification technology.
NANOSPHERE/TAKARO BIO FORM DEVELOP/DISTRIBUTE ALLIANCE by Worldwide Biotech
The gene copying appears to take place as a result of treatment: When the team looked at 16 prostate tumor samples taken from the same patients prior to therapy, they found no such gene amplification.
Gene copying aids prostate tumor growth by Fackelmann, Kathy A. / Science News
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