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glycogen |
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glycogen [ˈglaɪkəʊdʒən -dʒɛn] n (Life Sciences & Allied Applications / Biochemistry) a polysaccharide consisting of glucose units: the form in which carbohydrate is stored in the liver and muscles in man and animals. It can easily be hydrolysed to glucose Also called animal starch glycogenic [ˌglaɪkəʊˈdʒɛnɪk] adj
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Discovered by (OSI) Prosidion, OSI's diabetes and obesity team, PSN357 is a glycogen phosphorylase inhibitor (GPI), which is designed to rapidly lower blood glucose levels by preventing glycogen breakdown to glucose in the liver. Nasdaq: OSIP) announced today that it has initiated a Phase IIa clinical trial for its glycogen phosphorylase inhibitor, PSN357, which the company is developing for type 2 diabetes. Other product candidates include a glycogen phosphorylase inhibitor currently in a Phase I clinical trial and a glucokinase activator scheduled to enter a Phase I clinical trial in 2006. |
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