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glycosaminoglycan |
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It is worth noting that GlcA/N-acetyl-galactosamine is the repeating disaccharide found in the glycosaminoglycan moiety (chondroitin sulfate, dermatan sulfate) of proteoglycans, which are major constituents of the extracellular matrix. Weight bearing controls glycosaminoglycan concentration and articular cartilage thickness in the knee joints of young beagle dogs. Absence of the enzyme allows a complex sugar called glycosaminoglycan to accumulate in cells in the brain and throughout the body. |
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