Therefore different cell lines containing different repertoires of enzymes will glycosylate
the same protein in a cell specific manner (18).
Through genetic modifications to Pichia, RCT and VIB have created new strains which homogeneously glycosylate
proteins in a human-like manner.
We have spent the last five years engineering yeast cell lines that perform human glycosylation, which now allows us to glycosylate
proteins with unprecedented control and uniformity.