glycosylation


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gly·co·sy·la·tion

 (glī′kō-sĭ-lā′shən)
n.
The addition of saccharides to proteins or lipids to form a glycoprotein or glycolipid.

[glycose, a monosaccharide (variant of glucose) + -yl + -ation.]

gly·co′sy·late′ v.

glycosylation

(ˌɡlaɪkəʊsəˈleɪʃən)
n
(Biochemistry) the process by which sugars are chemically attached to proteins to form glycoproteins
[from glycosyl radical derived from glycose + -ation]
References in periodicals archive ?
com)-- Creative BioMart, a global leader in the supply of high quality protein products and efficient protein manufacturing techniques, today announced a major expansion of its Protein Glycosylation Labeling Service capacities as a response to rising customer needs and market demands for characterizing glycan structure and monitoring glycan profiles.
Since 1976, I have consistently devoted my effort to finding new glycosylation reactions as basic and general tools for maintaining glyco-science.
In the following, we will use the term "(NT-) proBNP" (NT-proBNP and/or proBNP) for better reading purposes, since the glycosylation positions are true for both peptides.
Hisashi Ietsugu) has received the 14th Annual Merit Award from the Minister of Economy, Trade and Industry for Collaborative Achievement Between Industry, Academia and Government for the practical realization of a system for diagnosing hepatic fibrosis using glycosylation, developed in collaboration with the National Institute of Advanced Industrial Science and Technology, or AIST (Tsukuba HQ: Tsukuba, Ibaraki Prefecture, Japan; President: Ryoji Chubachi).
The 17 chapters explore simple and complex carbohydrates and glycoconjugates; methods of structural analysis of glycosaminoglycans, applications of these methods for identification of lysosomal storage diseases, and participation in the development of Lyme disease; the role of viral envelope protein glycosylation in the pathogenesis of influenza A virus; the application of lectin histochemistry in the diagnosis of lysosomal storage diseases; computational approaches for studying carbohydrate-lectin interactions in infection; the pathogenic effects of altered sialylation of specific glycoconjugates in genetic diseases; sialyltransferase regulation of cancer-associated O-glycans; and the history of pectin study, chemistry, and medicinal uses of pectin.
In addition, although the HE proteins of human influenza C and C/OK viruses contain 7 and 6 potential glycosylation sites, respectively, D/bovine/ France/2986/2012 has just 5: at positions 28, 54, 146, 346, and 613 (ATG numbering), identical to 5 of the 6 identified for C/OK virus.
has introduced a new protein quality supplement called EX-CELL Glycosylation Adjust (Gal+), designed as a supplement for biological drug production, including biosimiliars.
Glycosylation of the HA gene is important for neutralization of the antigenic sites, (25) proper folding of the proteins, and has big influence on the antigenicity and immunogenicity of the HA glycoprotein.
The product is a host cell line for producing recombinant antibodies that combines the power of BioWa's engineered glycosylation POTELLIGENT Technology with the advantages of Lonza's GS Gene Expression System, which includes pre-eminent host cell line, CHOK1SV.
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