goblet cells


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Related to goblet cells: Paneth Cells, Crypts of Lieberkuhn

goblet cells

Goblet-shaped cells producing mucus and found in mucous membranes.
References in periodicals archive ?
Goblet cells are typically scattered among columnar cells and regulate local intestinal immune functions via specific or nonspecific immune mechanisms (Gaskins 1996; Guet al 2002).
2) Mucins, secreted by the goblet cells and epithelial cells, trap and clear allergens and pathogens.
coli were groups, were surrounded by moderately electron-dense material, which appears to be the secret of Goblet cells.
With large quantities of goblet cells, which help control the immune response to proteins found in food, scientists could study food allergies; with enteroendocrine cells, which release hunger hormones, they could test new treatments for obesity.
This gene has been detected in goblet cells within the tracheal and bronchial epithelium of mice when metaplasia of mucous cells is present (Leverkoehne and Gruber 2002) and is thought to play a role in the mucus hyper-secretion seen in chronic obstructive pulmonary disease (COPD) and CF in humans (Rogers 2003; Shale and Ionescu 2004).
The goblet cells (mucus-producing), evidenced by PAS histochemical method, are arranged along the entire length of the intestinal tract; besides that their frequency are sharply higher at the final portion of the tract.
Immunohistochemistry revealed that the PLUNC-positive cells were mainly expressed in nasal mucosa epithelium, in goblet cells, and especially in glandular epithelium.
Mucous cell metaplasia, the increase in the number of goblet cells and amounts of intraepithelial mucus storage, was induced by allergen in both pulmonary and nasal airways and decreased by treatment with gammaT.
Presence of nerves and their receptors in mouse and human conjunctival goblet cells.
Current smokers also had more mucous-producing goblet cells in their epithelium and, the epithelial cell layer contained more mucus protein overall, when compared to never-smoking asthmatics.
The dryness results in part from a loss of goblet cells, which reappear after vitamin A deficiency is corrected.
Hunt (1973) grouped the many different secretory cell types into two main categories: (a) acid mucin cells and (b) goblet cells.