goitrogen


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goitrogen

(ˈɡɔɪtrədʒən)
n
(Pathology) pathol a substance that causes the formation of goitre
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.goitrogen - any substance (such as thiouracil) that induces the formation of a goiter
chemical compound, compound - (chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight
References in periodicals archive ?
Induction of increased testis growth and sperm production in adult rats by neonatal administration of the goitrogen propylthiouracil (PTU): the critical period.
Thiocyanate has also been implicated as a goitrogen, as shown in a previous study from India (5).
Growth rate is reduced in chicken following goitrogen administration (Rosebrough and McMurtry, 2003).
With the replacement of iodine in bread dough by the goitrogen bromine in the early 1980s, the average iodine intake was reduced below the RDA of 150 mcg and the rate of breast cancer increased to 1:8 (absorption of iodine from bread is much better than from iodized salt).
The amount of thiocyanate in the urine is also a good indicator for the presence of goitrogen in foods (25).
Firstly, there are several anti-nutrition elements in full fat or dehulled soybean meal such as hemaglutinin, goitrogen and protease inhibitor that could inhibit the activity of trypsin and chymotrypsin (Dabrowski and Kozak, 1979).
Because PBDEs have the ability to interfere with thyroid hormone (TH) homeostasis, we included a reference group for TH-mediated effects by adding the goitrogen 6-n-propyl thiouracil (PTU) in the drinking water of pregnant females.
We previously showed that low maternal TH, produced experimentally by goitrogen treatment, can alter gene expression in the fetal cortex before the onset of fetal thyroid function (Dowling et al.
These tumors are readily induced by many genotoxic carcinogens, but they may also be induced by virtually any nongenotoxic goitrogen in these rodent species.
Direct neonatal treatment with thyroid hormone has the same effect, whereas treatment with the goitrogen propylthiouracil blocks the increase in hippocampal glucocorticoid receptor binding usually observed after handling (49).
Thermal processing of soy milk destroys biologically active anti-nutritional components of soybean like trypsin inhibitors, urease, hemagglutinins, goitrogens and saponins.