granulocyte colony-stimulating factor


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Related to granulocyte colony-stimulating factor: GCFS, rhG-CSF

granulocyte colony-stimulating factor

n. Abbr. G-CSF
1. A cytokine secreted by a variety of cell types that stimulates progenitor cells in the bone marrow to produce granulocytes, especially neutrophils.
2. A recombinant form of this cytokine, such as the drug filgrastim.
References in periodicals archive ?
Sometimes, treatment with a medication called granulocyte colony-stimulating factor, or GCSF, also may be used to help the body rebuild its supply of neutrophils.
Growth factors, including granulocyte colony-stimulating factor and erythropoietin, and transfusion support were available to all participants.
F-627 is a recombinant human granulocyte colony-stimulating factor (rhG-CSF) dimer with a best-in-class potential to manage CIN in cancer patients.
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) secretion by adherent monocytes measured by quantitative immunoassays.
Granulocyte colony-stimulating factor (G-CSF) exerts anti-inflammatory and antiapoptosis effects and stimulates the proliferation of neural stem and progenitor cells in the brain.
Granulocyte colony-stimulating factor attenuates oxidative stress-induced apoptosis in vascular endothelial cells and exhibits functional and morphologic protective effect in oxygen-induced retinopathy.
Abnormal laboratory values can include leukocytosis and anemia secondary to tumor production of granulocyte colony-stimulating factor (G-CSF) and interleukin-6, respectively.
Methods used to treat thin endometrium include hysteroscopic adhesiolysis, estrogen treatment, vasoactive measures, intrauterine infusion of granulocyte colony-stimulating factor, and regenerative medicine.
Granulocyte colony-stimulating factor (G-CSF) is a member of the cytokine family of growth factors.
Filgrastim is a recombinant human granulocyte colony-stimulating factor with several clinical uses, including aiding recovery from neutropenia in cancer patients undergoing chemotherapy.
A study reported in The American Journal of Gastroenterology found a benefit for the administration of granulocyte colony-stimulating factor (GCSF) in patients with severe alcoholic hepatitis, a condition with high short-term mortality.
The ODD was granted for use of BL-8040, in combination with granulocyte colony-stimulating factor (G-CSF), to mobilize human stem cells from the bone marrow to the peripheral blood for collection for autologous or allogeneic (donor-based) transplantation.

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