granulocyte-macrophage colony-stimulating factor


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Related to granulocyte-macrophage colony-stimulating factor: GM-CSF

granulocyte-macrophage colony-stimulating factor

n. Abbr. GM-CSF
1. A cytokine secreted by a variety of cell types that stimulates progenitor cells in the bone marrow to produce granulocytes (especially neutrophils) and macrophages.
2. A recombinant form of this cytokine, such as the drug sargramostim.
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SELLAS' Phase 2 double-blinded, randomized (1:1) study compared WT-1 analog peptides vaccine in combination with Montanide-adjuvant + Granulocyte-macrophage colony-stimulating factor (GM-CSF), versus Montanide-adjuvant + GM-CSF in patients with MPM who had previously completed combined modality therapy.
18), in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least a partial response to prior first-line multiagent, multimodality therapy.
oil (GCO) on the synthesis of collagen, elastin, and glycosaminoglycans (GAG) and in the release of transforming growth factor-beta1 (TGF-beta1) and granulocyte-macrophage colony-stimulating factor (GM-CSF) by human skin fibroblasts.
com)-- Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a protein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts.
Several studies suggest that a number of cytokines are involved in the development of blood hypereosinophilia in cancer patients, particularly interleukin-5 (IL-5) and granulocyte-macrophage colony-stimulating factor (GM-CSF) (1-3,6,7).
The vaccine regimen included a DNA prime vaccine that co-expressed HIV proteins and granulocyte-macrophage colony-stimulating factor (GM-CSF).
The nutraceuticals garlic, glutamine, IP6 (inositol hexaphosphate), and AHCC (active hexose correlated compound) and the pharmaceuticals interferon-alpha and granulocyte-macrophage colony-stimulating factor also stimulate NK cell activity.

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