sarcomas are solid tumors of myelocytic origin associated with both acute and chronic myelocytic leukemia or other myeloproliferative disorders (Krishnamurthy, Nusbacher, Elguezabal, & Seligman, 1976).
All cell lineages in myeloid hematopoiesis can be involved, including erythrocytic, granulocytic
, and megakaryocytic cell lines.
CML is a malignant proliferation of predominantly granulocytic
lineage and is due to the presence of the Philadelphia chromosome, which is a sine qua non for the diagnosis.
Krause (director of infectious disease at Connecticut Children's Medical Center) and Andrew Spielman (director of tropical medicine at Harvard University School of Public Health), evaluated recurrent and chronic cases of Lyme disease within a population endemic for Borrelia burgdorferi, human granulocytic
anaplasmosis, and Babesia microti, pathogens carried by the common deer tick.
Admission laboratory data included a hemogram with mild leukocytosis with polymorphonuclear granulocytic
predominance; serum transaminases were minimally elevated, and amylase and lipase were normal.
After a routine physical for a job in July 2000, Jeff Bateman discovered he had chronic myelogenous leukemia -- also called chronic granulocytic
leukemia or CML.
A nucleic acid encoding the receptor was isolated from a human granulocytic
cell library and antibodies generated against the polypeptide revealed expression in a variety of tissues including heart, placenta, and lung.
microti infection and Ehrlichia infection, particularly human granulocytic
ehrlichious and Lyme borrelosis are two tick-borne pathogens that infect more humans and animals every year.
Comeback ends: Milos Holan, 27, a Czech defenseman who struggled to regain his health after being diagnosed three years ago with granulocytic
leukemia, a form of blood cancer, was released by the Ducks.
Only 2 months earlier, another team announced it had discovered in six people from Wisconsin and Minnesota an Ehrlichia species never before seen in humans, granulocytic
GCSF acts on its homodimeric receptor (GCSFR) to stimulate proliferation of granulocytic
progenitor cells and induce their survival and differentiation into neutrophils.