6] Causes of anaemia in HF include iron deficiency, renal insufficiency, haemodilution
due to activation of renin-angiotensin-aldosterone and vasopressin systems, infections such as HIV, and drugs that interfere with the synthesis of endogenous erythropoietin, e.
Drop in platelet count (PC) in cardiac surgery is mainly due to haemodilution
, platelet activation due to contact with extra corporeal circuit and heparin-induced thrombocytopenia (HIT).
This HL has been attributed to tissue hypoxia caused by haemodilution
and impaired oxygen delivery.
The use of plasma for priming the circuit has been challenged because it is associated with haemodilution
and eventually leads to increased bleeding and mortality; however, the use of circuit priming with plasma is common practice for us and we believe that our results support its potential beneficial effect, as reflected by the R values in the cohort following cardiopulmonary bypass.
9) should be demonstrated in vivo, with different degrees of haemodilution
and fluid combinations, but this first contribution will outline the importance of fluid administration in neurosurgery and haemostasis monitoring with a viscoelastic point-of-care.
36) A 6% level of transient hypocalcaemia (48 hours postoperatively) is lower than the 19-38% range quoted by a recent review and meta-analysis, (36) the varied timing from surgery to calcium assay may explain this wide margin (various authors assay serum calcium between 6 to 72 hours after surgery); however, calcium values generally may be influenced by perioperative factors like postoperative haemodilution
, handling of parathyroid gland leading to calcitonin release, urinary calcium excretion facilitated by surgical stress, Vitamin D deficiency and hungry bone syndrome.
It has been suggested that the decrease in the albumin contents might be attributed to increase blood volume that occurred due to haemodilution
during successful pregnancy.
But the disproportionate increase in plasma volume causes haemodilution
and it lowers the haemoglobin level.
Several factors cause a more profound systemic inflammatory response in neonates and infants compared to older children or adults: (1) the surface and the volume of the CPB circuit relative to the blood volume and patient size, (2) more frequent use of hypothermic circulatory arrest, and (3) more pronounced haemodilution
Initially decreased viscosity after haemodilution
improves venous return and cardiac preload, thereby increasing cardiac output.
Briefly, the current recommendations entail that the patient should abstain from foods and beverages for at least 6-12 hours before testing (8), in order to limit the unwanted effects of food ingestion and haemodilution
on a number of laboratory analytes (9-11).
The authors observed that in the subjects demonstrating an increase in Hbmass, isovolumic haemodilution
elicited a 5.