Conditions controlling the proliferation of haemopoietic
stem cells in vitro.
Such a level of service is not yet available in any country, and at best only 50% of the needs for haemopoietic
cell transplantation are currently satisfied.
A subset of patients with severe combined immunodeficiency followed up over the long term post haemopoietic
stem cell transplantation (33) exhibited severe cutaneous papillomatosis associated with either common [gamma]c receptor cytokine subunit or Janus kinase-3 (JAK-3) deficiency.
This is also known as meningeal carcinomatosis, and can be caused by primary neuro ectodermal tumours such as neuroblastoma, tumours of the haemopoietic
system such as lymphoma, or solid tumours metastasizing to the leptomeninges (e.
It is well recognised that at times of increased haemopoietic
demand, folic acid supplementation is indicated, but for some reason this is often forgotten when initiating treatment with iron in patients who are significantly anaemic.
50] value) and confirmed that the effect is owed to accelerated proliferation and differentiation of haemopoietic
stem cells, upgrading the level of WBC, maintaining the balance of each strain cell in the blood, and suggesting that swainsonine is also a commendable immunomodulator.
This trial will test whether the thymus, having been reactivated by Norwood Immunology's technology can, in the presence of donor haemopoietic
stem cells (the stem cells that form blood and immune cells), create a new immune system that is tolerant to that donor.
CD 34 is a surface glycophosphoprotein expressed on haemopoietic
stem and progenitor cells, small vessel endothelial cells and embryonic fibroblasts (6).
Pathology and Genetics, Tumors of Haemopoietic
and Lymphoid Tissues.
The incidence of drug-induced haematological dyscrasias also increases with age, more specifically with age-related declines in renal/hepatic function and haemopoietic
stem cell potential.
Doxorubicin (DXR; Adriamycin) is one of the effective and useful antineoplastic agents commonly used for the treatment of a variety of tumors including solid and haemopoietic
malignancies (Tan et al.
Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic
stem cell transplantation.