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heavy chain

   Also found in: Medical, Legal, Financial, Encyclopedia, Wikipedia 0.03 sec.
heavy chain
n.
The larger of the two types of polypeptide chains in immunoglobulins, consisting of an antigen-binding portion having a variable amino acid sequence, and a constant region that defines the antibody class.
heavy chain
n
(Medicine) Immunol a type of polypeptide chain present in an immunoglobulin molecule
heavy chain  (hv)
The larger of the two types of polypeptide chains in an immunoglobulin molecule. A heavy chain consists of an antigen-binding portion having a variable amino acid sequence, and a constant region that is different for each class of imunoglobulin. Each heavy chain is one of a Y-shaped identical pair and is attached along its variable region to a smaller light chain. Compare light chain.


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? Mentioned in ? References in classic literature
 
The dog rushed forth from a niche in the wall, shaking his heavy chain, and sniffing all round Cornelius in order so much the better to recognise him in case he should be ordered to pounce upon him.
The Black Tulip by Dumas, Alexandre View in context
They were succeeded by a clanking noise, deep down below; as if some person were dragging a heavy chain over the casks in the wine merchant's cellar.
A Christmas Carol by Dickens, Charles View in context
When she paid the coachman she took her money out of a hard steel purse, and she kept the purse in a very jail of a bag which hung upon her arm by a heavy chain, and shut up like a bite.
David Copperfield by Dickens, Charles View in context
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