helper T cell


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Related to helper T cell: cytotoxic T cell, B cell, Effector T cells

helper T cell

n.
Any of a class of T cells that are activated by interacting with antigen-presenting cells, such as a dendritic cells, and then function to activate other cells of the immune system, including B cells, cytotoxic T lymphocytes, and phagocytes. Activated helper T cells usually have CD4 receptors on the surface. Also called T-helper cell.

helper T cell


n.
any of a group of T cells that activate the immune system either by enhancing the production of antibody and other T cells or by mobilizing macrophages to engulf invading particles.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.helper T cell - T cell with CD4 receptor that recognizes antigens on the surface of a virus-infected cell and secretes lymphokines that stimulate B cells and killer T cells; helper T cells are infected and killed by the AIDS virus
T cell, T lymphocyte - a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells
References in periodicals archive ?
Researcher Dr Jane Steele said: "We found patients with pre-cancerous lesions most likely to progress to cervical cancer showed less immune activity from immune cells called helper T cells than women who were at much less risk.
Researchers now have evidence that CTLs indeed attack HIV in lymph tissue and seem to distinguish between healthy and infected helper T cells.
In HIV infection, CD4+ T cells, or helper T cells, are a major target for infection.
Also CD4 helper T cells are the cells that are targeted and eventually eliminated by HIV, the virus that causes AIDS.
Helper T Cells are activated by binding to an HTL specific epitope presented by cells in a similar fashion as CTL epitopes are presented.
DSP-7888 is an investigational cancer peptide vaccine containing peptides that induce Wilms' tumor gene 1 -specific cytotoxic T lymphocytes and helper T cells, which attack WT1-expressing cancerous cells found in various types of hematologic and solid cancers.
OCA-B was expressed in activated and re-activated helper T cells and was required, together with Oct1, for removal of repressive epigenetic marks from the Il2 gene.