helper T cell


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Related to helper T cell: cytotoxic T cell, B cell, Effector T cells

helper T cell

also helper cell
n.
Any of the T cells that carry the CD4 glycoprotein receptor on their surface and that when stimulated by foreign antigens release lymphokines that promote the activation and function of B cells and killer T cells. Also called CD4 cell, T4 cell, T-helper cell.

helper T cell


n.
any of a group of T cells that activate the immune system either by enhancing the production of antibody and other T cells or by mobilizing macrophages to engulf invading particles.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.helper T cell - T cell with CD4 receptor that recognizes antigens on the surface of a virus-infected cell and secretes lymphokines that stimulate B cells and killer T cells; helper T cells are infected and killed by the AIDS virus
T cell, T lymphocyte - a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells
References in periodicals archive ?
Also CD4 helper T cells are the cells that are targeted and eventually eliminated by HIV, the virus that causes AIDS.
Helper T Cells are activated by binding to an HTL specific epitope presented by cells in a similar fashion as CTL epitopes are presented.
Researcher Dr Jane Steele said: "We found patients with pre-cancerous lesions most likely to progress to cervical cancer showed less immune activity from immune cells called helper T cells than women who were at much less risk.
RANTES, MIP-1 alpha, MIP-1 beta) that compete with HIV particles for preferred entry sites on the surface of helper T cells, thereby thwarting the hallmark viral invasion of the helper T cell population.
Researchers now have evidence that CTLs indeed attack HIV in lymph tissue and seem to distinguish between healthy and infected helper T cells.
In HIV infection, CD4+ T cells, or helper T cells, are a major target for infection.
Using the antibodies, researchers slowed the functions of helper T cells that normally aid in production of antibodies but may "overhelp' in the case of SLE.
HIV's favorite hosts are white blood cells called helper T cells in which the virus docks with molecules on those cells called CD4 and CCR5.
Other metaphors popular among immunologists imbue immune system components with the ability to think, recognize and act - tolerance, surveillance, foreigness, helper T cells, rejection.