helper cell

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Related to helper cell: Effector T cells
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Noun1.helper cell - T cell with CD4 receptor that recognizes antigens on the surface of a virus-infected cell and secretes lymphokines that stimulate B cells and killer T cells; helper T cells are infected and killed by the AIDS virus
T cell, T lymphocyte - a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells
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References in periodicals archive ?
These treatments focus on the blockade of inflammatory cytokines, especially those that derive from T helper cell type 2.
The incidence of pneumocystis pneumonia has been found to be associated with a T helper cell deficiency (CD4 counts) of less than 200/ [micro]L.
Th stands for T helper cell, which is an important player in the immune system.
These findings show that Oct1 and OCA-B are involved in memory T cell function and are necessary for the helper cell memory response.
Objective: The aim of this proposal is to engineer biocompatible nanoparticles that deliver short interfering RNA (siRNA) to activated T cells (ATCs) for the downregulation of the Type 2 T helper cell (Th2) transcription factor GATA-3.
While the complete mechanism of immunomodulation by PLX cells requires further investigation, this study demonstrates how PLX cells might inhibit the immune responses of Type 1 T helper cell.
Effective cancer vaccines need to target dendritic cells to stimulate both parts of the cellular immune system; the helper cell system where inflammation is stimulated at the tumor site; and the cytotoxic T-lymphocyte or CTL response where immune system cells are primed to recognise and kill specific cells.
1 shows the differentiation of naive T cell into the three different T helper cell types i.
The current analysis was designed to evaluate the consistency of the association between acetaminophen and asthma and to investigate one of the proposed biological mechanisms for the link--specifically, that acetaminophen exposure contributes to the development of oxidant-induced airway inflammation caused by reduced concentrations of the antioxidant glutathione in the lung and stimulation of the T helper cell 2 response.
A model of human immunodeficiency virus infection in T helper cell clones.
However, the PHI group did exhibit stronger T helper cell responses, which led the researchers to suggest that "individuals treated in early infection may benefit from [therapeutic] strategies aimed at enhancing virus-specific CTL responses, whereas individuals treated later in infection may benefit from strategies aimed at enhancing HIV-1-specific T helper cell functions as well as broadening CTL responses to combat increased viral diversity.