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hemolysin |
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suis ST-7 expressed the proposed virulence markers muramidase-released protein (MRP), extracellular protein factor (EF), and hemolysin (named suilysin) (9-11) and was markedly more cytototoxic to human peripheral blood mononuclear cells (PBMC) than a representative ST-1 strain. But for something as complex as hemolysin, I think Bayley's come up with a fabulous experimental system. Strains that produce the thermostable direct hemolysin or the thermostable direct hemolysin-related hemolysin, which are encoded by tdh and trh genes, respectively, are considered pathogenic. |
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