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hepatotoxicity |
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| The mechanism of hepatotoxicity of HC/ZnO smoke is still unknown. This third option, initially strongly considered from prior recommendations (4), was not chosen because published case series suggested poor tolerance and unacceptable hepatotoxicity (8,9). Hepatotoxicity, or liver damage caused by medications and other chemical compounds, is the single most common reason leading to drug withdrawal or refusal of drug approval by the Food and Drug Administration (FDA). |
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