hexokinase


Also found in: Medical, Acronyms, Encyclopedia, Wikipedia.

hexokinase

(ˌhɛksəʊˈkaɪneɪz; ˌhɛksəʊˈkaɪneɪs)
n
(Biochemistry) an enzyme that catalyses the transfer of phosphate from ATP to glucose

hex•o•ki•nase

(ˌhɛk səˈkaɪ neɪs, -neɪz)

n.
an enzyme that catalyzes the phosphorylation of hexose sugars.
[1925–30; hexo (se) + kinase]
References in periodicals archive ?
Hypoxia stimulates proliferation of human hepatoma cells through the induction of hexokinase II expression.
Effects of low-frequency stimulation on soluble and structure-bound activities of hexokinase and phosphofructokinase in rat fast-twitch muscle.
Mild Alkalization Acutely Triggers the Warburg Effect by Enhancing Hexokinase Activity via Voltage-Dependent Anion Channel Binding.
Ziegenhorn, "UV-methods with hexokinase and glucose-6-phosphate dehydrogenase," in Methods of Enzymatic Analysis, H.
Shulga, "Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity," Cancer Research, vol.
sup][35] It has been reported that SIRT3 activates oxidative phosphorylation and inhibits glycolysis and destabilize the association of hexokinase II with the mitochondria via inactivation of cyclophilin D.
Glucose was analyzed by hexokinase method on a random access clinical chemistry analyzer (Hitachi-902).
The activity of malate dehydrogenase (MDH), [beta]-hydroxyacyl-coenzyme A dehydrogenase ([beta]HAD), hexokinase (HK), pyruvate kinase (PK), and lactate dehydrogenase (LDH) was measured at 340 nm by monitoring the production or consumption of the reduced form of nicotinamide adenine dinucleotide (NADH) or the reduced form of nicotinamide adenine dinucleotide phosphate (NADPH).
According to research by scientists at Duke and Northwestern Universities, the hexokinase team actually has a fifth player.
Fasting plasma glucose level was measured by the hexokinase glucose-6-phosphate dehydrogenase procedure.
Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.