histocompatibility complex


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Noun1.histocompatibility complex - a family of fifty or more genes on the sixth human chromosome that code for proteins on the surfaces of cells and that play a role in the immune response
category, class, family - a collection of things sharing a common attribute; "there are two classes of detergents"
References in periodicals archive ?
Trogarzo binds primarily to the second extracellular domain of the CD4+ T receptor, away from major histocompatibility complex II molecule binding sites.
Scientists from UEA and Dalhousie University studied how Guppy fish (Poecilia reticulata) adapt to survive by studying their immune genes, known as the Major Histocompatibility Complex or MHC genes.
It also represents a manifestation of the immune systems function to distinguish self from non-self and reflects recognition of foreign antigens including the products of the Major Histocompatibility Complex (MHC) and minor Histocompatibility genes.
The first signal required for T-cell activation is antigen presentation via the major histocompatibility complex on antigen-presenting cells (APCs).
The immunohistochemical staining for major histocompatibility complex class 1 was equivocal.
In humans, major histocompatibility complex controlled by the genes located on chromosome 6 is responsible for ensuring compatibility between donors and recipients.
Cathepsin S is involved in the assembly of the major histocompatibility complex II protein, and by interfering with this process, the effector T-helper cell response may be muted and T-cell interaction with B cells may be decreased.
2) One of these risk genes, on chromosome 6, is in the major histocompatibility complex and has the strongest association with schizophrenia (P = [10.
It also involves in forming major histocompatibility complex (MHC class I or MHC I) or like heterodimers, covering from antigen presentation to immune homeostasis.
The major histocompatibility complex (MHC) region, containing a number of immune related genes, is one of the most significant genomic locations in animals due to its association with immune responses.
There is substantial work done on the major histocompatibility complex (MHC) class II genes to understand the level of polymorphism in different mammals although a limited work have been done on camel DRB3 gene.