homatropine


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ho·mat·ro·pine

 (hō-măt′rō-pēn′)
n.
An anticholinergic drug derived from tropine, C16H21NO3, used in its bromide form to dilate the pupil of the eye and in combination with hydrocodone to prevent overdosage of that drug.

References in periodicals archive ?
A fixed dilated pupil occurred in 1 eye due to prolonged use of Homatropine after the operation in PK.
M2 EQUITYBITES-February 20, 2017-Perrigo awarded US FDA final approval for hydrocodone bitartrate and homatropine methylbromide oral solution
M2 PHARMA-February 20, 2017-Perrigo awarded US FDA final approval for hydrocodone bitartrate and homatropine methylbromide oral solution
They vary in potency and duration of action, with the effects of cyclopentolate hydrochloride 1% lasting up to 24 hours compared to homatropine hydrobromide or atropine sulfate whose effects can continue for up to three or seven days, respectively.
The patient was initially given topical 1% topical prednisolone acetate (every hour while awake) and 1% homatropine (2*/d).
This class includes four anticholinergic agents: atropine, cyclopentolate (Cyclogyl), homatropine, and tropicamide (Mydriacyl).
Although there are no reports of teratogenic effects from topical use, minor fetal malformations have been reported from systemic use of phenylephrine, atropine and homatropine, and there is relative contraindication for their ophthalmologic use.
Several pharmaceutical products containing hydrocodone in combination with acetaminophen, aspirin, other NSAIDs, and homatropine are approved by the FDA for use as analgesics for pain relief and for the symptomatic relief of cough and upper respiratory symptoms associated with allergies and colds; and
A postmydriatic test was done after 3 days if retinoscopy had been done under homatropine and after 2 weeks if it had been done under atropine.
There are 81 products that combine hydrocodone with acetaminophen or ibuprofen and 12 cough suppressants that combine hydrocodone with chlorpheniramine, homatropine, or pseudoephedrine, according to the FDA.