homogentisic acid

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Noun1.homogentisic acid - an acid formed as an intermediate product of the metabolism of tyrosine and phenylalanine
acid - any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
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Ochronosis is a syndrome caused by the accumulation of homogentisic acid (HGA) in connective tissues.
The homogentisic acid when in excess gets polymerized and accumulates into connective tissues leading to dark pigmentation of tissues.
19] In melanotic RCC, dark-brown endogenous pigments can be found; the kidney may appear black one, and the differential diagnosis may be hemosiderin, homogentisic acid and lipofuscin.
Alkaptonuria is a metabolic disorder caused by the lack of homogentisic acid oxidase enzyme.