homolog


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hom·o·log

or hom·o·logue  (hŏm′ə-lôg′, -lŏg′, hō′mə-)
n.
Something that is homologous, as an organ, body part, or gene.

[French homologue, from Greek homologon, neuter of homologos, agreeing; see homologous.]
References in periodicals archive ?
Kovach continued, "Investigators at the Terry Fox Cancer Center, Vancouver, BC, reported at the American Society of Hematology in December 2014, that LB-100 and a lipid-soluble homolog of LB-100 (LB-102) are active against imatinib-naive and imatinib-resistant human chronic myelogenous leukemia cells (CML) (Lai et al (2014) Blood 124:(21)899).
Characterization of a canine homolog of hepatitis C virus.
Molecularly, type 1 tumors often exhibit mutations in phosphatase and tensin homolog (PTEN), Kras, and beta-catenin.
Ras homolog enriched in brain (Rheb) and FKBP38 are two important regulatory proteins in the mTOR pathway.
Professional standards and guidelines for reporting known variants in established and disease-causing genes such as BRCA1 (breast cancer 1, early onset) or MLH1 (mutL homolog 1) are clear, but how will novel and rare mutations be reported?
Thanks to our work, we think the sex peptide signal goes to a region of the fly's brain that is the homolog of the hypothalamus, which has been know for many years to be central in controlling sexual receptivity in vertebrates," explained co-lead author Dr Mark Palfreyman of the Research Institute of Molecular Pathology in Vienna, Austria.
Mark Palfreyman, from Research Institute of Molecular Pathology in Vienna, expalined in another Neuron paper that according to them the sex peptide signal went to a region of the fly's brain that was the homolog of the hypothalamus, which has been know for many years to be central in controlling sexual receptivity in vertebrates.
2,5,6) Enhancer of zeste homolog 2 (EZH2), the catalytic subunit of polycomb repressive complex (PRC2), acts as a histone methyltransferase by adding 3 methyl groups to lysine 27 of histone 3 (H3K27).
Subsequent tuning of the reactivity and specificity of the electrophile resulted in the discovery of a class of highly selective Btk inhibitors within the cysteine homolog family.
In the new work, Morris and his colleagues showed that pseudogenes can influence the activity of a human gene known as the phosphatase and tensin homolog (PTEN).
The topic of his research was Functional Characterization of Vti homolog 1b in Amblyomma americanum ticks.