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human chorionic gonadotrophin |
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| A reduction in circulating levels of estrogens and insulin-like growth factor 1 (IGF-1) and/or elevated levels of progesterone, androgens, human chorionic gonadotrophin, IGF-1 binding proteins 1 and 3, cortisol, and insulin have been associated with reduced risk. The two new Down syndrome reagents are designed to measure the free beta subunit of human Chorionic Gonadotrophin ("Free hCG[eth]") and Pregnancy Associated Plasma Protein A ("PAPP-A"), respectively, in maternal serum, which are important markers of Down syndrome. Breeding was induced by subcutaneous injection of human chorionic gonadotrophin. |
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