hyaluronidase


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Related to hyaluronidase: hyaluronic acid

hy·a·lu·ron·i·dase

 (hī′ə-lo͝o-rŏn′ĭ-dās′, -dāz′)
n.
An enzyme that catalyzes the breakdown of hyaluronic acid in the body, thereby increasing tissue permeability to fluids. Also called spreading factor.

hyaluronidase

(ˌhaɪəlʊˈrɒnɪˌdeɪs; -ˌdeɪz)
n
(Biochemistry) an enzyme that breaks down hyaluronic acid, thus decreasing the viscosity of the medium containing the acid
[C20: hyalo- + Greek ouron urine + -id3 + -ase]

hy•a•lu•ron•i•dase

(ˌhaɪ ə lʊˈrɒn ɪˌdeɪs, -ˌdeɪz)

n.
an enzyme that decreases viscosity in the tissue spaces of the body by breaking down hyaluronic acid: used as an ingredient for diffusing injected drugs.
[1935–40; hyaluron(ic acid) + -id- + -ase]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.hyaluronidase - an enzyme (trade name Hyazyme) that splits hyaluronic acid and so lowers its viscosity and increases the permeability of connective tissue and the absorption of fluids
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
References in periodicals archive ?
This in vitro study, published in the August issue of Clinical, Cosmetic and Investigational Dermatology, showed that the sodium copper chlorophyllin complex contained in Phytochromatic MD Complex, has strong hyaluronidase inhibitory activity.
Hyaluronidase (CAS 37326-33-3) Market Research Report 2013 presents comprehensive data on Hyaluronidase markets globally and regionally (Europe, Asia, North America etc.
Tests indicated that a 97% inhibition of hyaluronidase was achieved with the use of AquaMax at a concentration of 0.
Hyaluronidase inhibition assay was studied in vitro using bovine testicular hyaluronidase and human umbilical cord hyaluronic acid.
Hyaluronidase is an enzyme which degrades hyaluronan (HA) and has diverse clinical applications resulting from its ability to facilitate the dispersion and/or absorption of an array of medications and fluids.
Hyaluronidase activity was determined according to the native method of Reissig et al (1955) and reinvestigated Reissig et al method.
Thus, inhibition of hyaluronidase by BioCell Collagen II implies that its ingestion may promote hydrated, younger-looking appearance from the inside out via helping maintain the healthy size and levels of HA.
HYLENEX is the first and only human recombinant hyaluronidase therapeutic product and is available from Baxter in one milliliter single-dose vials containing 150 units of hyaluronidase.
SALT LAKE CITY -- Recombinant human hyaluronidase makes it possible to safely hydrate patients subcutaneously with a gravity line feed at flow rates approaching 500 cc/hour, according to a preliminary study presented at the annual meeting of the American Academy of Hospice and Palliative Medicine and the Hospice and Palliative Nurses Association.
Halozyme has received FDA approval for two products: Cumulase, the first and only recombinant human hyaluronidase for cumulus removal in the IVF process, and Hylenex for use as an adjuvant to increase the absorption and dispersion of other injected drugs.
The company has received FDA approval for two products: Cumulase, the first and only recombinant human hyaluronidase for cumulus removal in the IVF process; and Hylenex, for use as an adjuvant to increase the absorption and dispersion of other injected drugs.
If the fluid is viscous, hyaluronidase lyophilized powder (Type V from sheep testes from Sigma H6254) should be used to treat a portion of the viscous fluid for cell counts.