Hematopoietic cell transplantation (HCT) form healthy donors is applied to LSD patients in order to repopulate the recipient myeloid compartment, including CNS microglia, with donor-derived cells expressing the defective functional hydrolase
Background: Soluble epoxide hydrolase
(sEH) has been demonstrated to be a key enzyme involved in the pathologic development of several cardiovascular diseases and inflammation, and inhibition of sEH is therefore very helpful or crucial for the treatment of ischemia-reperfusion injury, cardiac hypertrophy, hypertension and inflammation.
The gastrointestinal microbiota composition is influenced by bile salts and in turn, bile salts themselves are chemically modified in the gut by bacterial enzymes such as bacterial bile salt hydrolase
Importantly, the research team discovered that an enzyme called alpha/beta hydrolase
domain-6 (in short ABHD6) breaks down monoacylglycerol and thus negatively controls insulin release.
C-serum extracted from fresh Hevea brasiliensis latex has been identified to contain lipid acyl hydrolase
(LAH), a subtype of lipase which may play an important role in the defense mechanism against plant parasites [1, 2].
The crystal structure of endoglucanase CelA, a family 8 glycosyl hydrolase
from Clostridium thermocellum.
However, no isolate showed bacteriocin, hemolytic or bile salt hydrolase
glutathione transferases, epoxide hydrolase
, NAD(P)H: quinone reductase, and glucuronosyltransferases] is a powerful strategy for achieving protection against carcinogenesis, mutagenesis, and other forms of toxicity of electrophiles and reactive forms of oxygen.
Prostate-specific membrane antigen (PSMA; also known as folate hydrolase
1, glutamate carboxypeptidase II or NAALA-Dase) presents a novel endothelial target.
We used flavobacterium which produces organophosphorus hydrolase
(OPH) as a model to modify cells and biomolecules magnetically", Seyed Morteza Robatjazi, PhD student of chemical engineering-biotechnology, said in an interview with the INIC.
cholerae is essential for (p)ppGpp hydrolase
Isolation of methyl parathion-degrading strain M6 and cloning of methyl parathion hydrolase