Asthma is a reversible airway obstruction that is characterized by hyperirritability
of the airways, airway inflammation and remodeling of the airways that is associated with constriction of airway smooth muscle, hyper secretion of mucus, edema and thickening of the basement membrane underlying the airway epithelium .
Prednisone is another drug used to treat leprosy reactions and that might cause metal disorders, such as: euphoria, mood changes, severe depression with psychotic symptoms, hyperirritability
TDH advised hospitals to report cases in which a diagnosis of NAS was assigned to an infant based on a clinical withdrawal syndrome, with symptoms such as feeding difficulty, sleep disturbance, hyperirritability
, or seizures.
On digital palpation a point of hyperirritability
or severe point tenderness is found at the insertion of the plantar fascia into the calcaneus.
7-10) ASD severity can be defined by the child's cognitive level, ability to relate to surroundings, hyperirritability
, self-injurious behaviors, and affective responses which can be assessed using parent/clinician reports on instruments such as Autism Behavior Checklist (ABC), (11) and Childhood Autism Rating Scale (CARS).