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Related to hyperkeratotic: hyperkeratosis, keratoacanthoma, acanthosis, exophytic


n. pl. hy·per·ker·a·to·ses (-sēz)
Hypertrophy of the cornea or the horny layer of the skin.

hy′per·ker′a·tot′ic (-tŏt′ĭk) adj.


(Pathology) pathol overgrowth and thickening of the outer layer of the skin
hyperkeratotic adj


(ˌhaɪ pərˌkɛr əˈtoʊ sɪs)

1. proliferation of the cells of the cornea.
2. a thickening of the horny layer of the skin.
hy`per•ker`a•tot′ic (-ˈtɒt ɪk) adj.
References in periodicals archive ?
Confluent and reticulated papillomatosis (CARP) of Gougerot and Carteaud, also known as Gougerot-Carteaud syndrome, is an uncommon skin disorder of young individuals characterized by hyperkeratotic or verrucous brown papules or plaques that coalesce centrally and by a reticulated pattern peripherally.
On local examination of the skin, a single hyperkeratotic irregular shaped scaly plaque measuring 5 x 3 cm was present over the right foot adjoining the sole.
It is generally divided into three categories: diffuse PPK, with involvement of the whole palmoplantar surface; focal and striate PPK, usually located mainly on pressure points; and punctate PPK, featuring multiple small hyperkeratotic papules, nodules, or spicules.
The cutaneous lesions presented as hyperkeratotic, symmetrical, and desquamatory plaques on the whole body (figure).
Hyperkeratotic lesions such as leukoplakia can pose diagnostic challenge, as they yield scanty cellularity on scrape smear, which may erroneously appear benign on cytology, which compromises the accuracy of the technique.
Materials and Methods: 90 patients with tobacco associated hyperkeratotic red and white lesion, ulcerative lesion, and frank malignancy included in study.
It is characterised clinically by hyperkeratotic papules or plaques with raised and advancing edge, which histologically corresponds to a column of parakeratotic cells.
1,2) An earlier texbook even suggests rubbing on coarse granite or coarse bricks for excessive hyperkeratotic feet.
In Brazil, due to the high number of leprosy, physicians should be aware of the possibility of CS in leprosy patients who develop widespread hyperkeratotic eruptions.
Therefore, the aim of this study was to estimate heritability as well as genetic and environmental correlations between 305-day milk yield (Milk305), milk yield in the first test-day (Firstmilk), mastitis occurrence (Mast), number of mastitis occurrence (NumMast), days sick (DS), hyperkeratosis (Hup), number of hyperkeratotic teats (NumHyp) and sum of the degree of hyperkeratotic teats (DegHyp) in Holstein cows.
In some areas, the mucosal epithelium was hyperkeratotic and covered with a fibrinonecrotic inflammatory infiltrate admixed with similar yeasts and pseudohyphae, colonies of coccoid- and rod-shaped bacteria, and plant material.
Actikerall is indicated for the topical treatment of slightly palpable and/or moderately thick hyperkeratotic actinic keratosis, a pre-cancerous patch of thick, scaly, or crusty skin.