Upon approval, Pronova and Takeda are confident that Lotriga will be able to contribute to patients living with hyperlipidemia
in Japan as a valuable new treatment option.
was designed as a superiority trial for the primary endpoint, LDL-C reduction, and evaluated the adult population age 18-80 with primary hyperlipidemia
or mixed dyslipidemia.
5) The USPSTF cites a lack of evidence regarding whether or not the identification and treatment of hyperlipidemia
during youth, would necessarily improve cardiovascular outcomes in adulthood.
It appears that sanchi is likely to reduce the risk of coronary heart disease associated with oxidative stress and hyperlipidemia
While the researchers found that diabetes and hypertension increased the risk of OAG, the study showed that hyperlipidemia
actually reduced by 5 percent the risk for developing the disease.
The patent relates specifically to the treatment of hyperlipidemia
or hypercholesterolemia, including severe hypercholesterolemia, using step-wise, increasing doses of lomitapide.
was defined as a total cholesterol level of at least 6.
is strongly associated with the PI regimen, we focused on the subgroup of 148 patients receiving PI as a component of their antiretroviral therapy, and we analyzed their lipid profile changes over the 5-year follow-up period.
Research: Researchers performed a multicenter, randomized, placebo-controlled, parallel-group trial of 143 patients with hypercholesterolemia or combined hyperlipidemia
having a baseline LDL cholesterol of 150 mg/dl and either no or one cardiovascular risk factor other than known coronary heart disease, or baseline LDL-C levels of between 150 and 189 mg/dl and two or more risk factors.
J-LIT, which covers approximately 50,000 hyperlipidemia
patients in Japan, is designed to examine the correlations among the administration of simvastatin, serum lipid levels, and risk of ischemic disorder.
CoQ10 and CoQ10H2 are important elements of the electron transport chain and may be useful biomarkers of oxidative stress, thus of primary importance in clinical diagnosis of diseases such as atherosclerosis, hyperlipidemia
and coronary artery disease.
Schizophrenia patients exposed to the new-generation antipsychotic olanzapine (Zyprexa) and, to a lesser extent, clozapine (Clozaril) appear to have a roughly 20% greater chance of developing new-onset hyperlipidemia
, compared with those using older antipsychotics.