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hypersensitivity reaction

   Also found in: Medical, Legal, Financial, Encyclopedia, Wikipedia, Hutchinson 0.06 sec.
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Noun1.hypersensitivity reaction - an inappropriate and excessive reaction to an allergen (as pollen or dust or animal hair or certain foods); severity ranges from mild allergy to severe systemic reactions leading to anaphylactic shock
hives, nettle rash, urticaria, urtication - an itchy skin eruption characterized by weals with pale interiors and well-defined red margins; usually the result of an allergic response to insect bites or food or drugs
allergic reaction, allergy - hypersensitivity reaction to a particular allergen; symptoms can vary greatly in intensity
anaphylaxis - hypersensitivity reaction to the ingestion or injection of a substance (a protein or drug) resulting from prior contact with a substance
hypersensitivity - pathological sensitivity
allergic rhinitis - rhinitis caused by an allergic reaction


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The hypersensitivity reaction occurs in about 5% of patients starting abacavir overall, with people of African descent reporting it less frequently.
Initially noting dermal manifestations, consistent with an allergic contact dermatitis secondary to accelerators present in latex gloves, he later developed urticaria, flushing, and respiratory symptoms, consistent with a type I hypersensitivity reaction to latex.
Promethazine is used for treating hypersensitivity reactions and as an antiemetic and sedative in various settings, but the US FDA has advised the drug should be 'administered with caution' in paediatric patients younger than two years, after receiving reports of respiratory depression and apnoea, including fatalities, following the administration of promethazine tablets and rectal suppositories.
 
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